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The aim of this study was to analyze quality of life impairment in patients with negative shoulder values after breast cancer treatment. A prospective study was performed in 48 consecutive patients treated for breast cancer by surgery and radio/chemotherapy. All patients were evaluated by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and EORTC QLQ-Br18 scales of shoulder function and self-perception of shoulder appearance at baseline and 1 year. Patients were divided into two groups: those with a positive and those with a negative shoulder value. The positive shoulder value group (n = 31) was compared with the negative shoulder value group (n = 17) for the QLQ-C30 and EORTC QLQ-Br18 values. One year after surgery, mean overall quality of life (QOL) values were higher than baseline for global QOL, role functioning, social functioning, and emotional functioning, whereas QOL scores remained stable for physical functioning and fatigue. Values were significantly higher in the positive shoulder value group than in the negative shoulder value group. This study shows that patients with a negative shoulder value have a lower quality of life than patients with a positive shoulder value. Therefore, the authors believe that patients with a
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